講座通知：Wiring & rewiring: circuit development and plasticity in the sensory cortices
題目：Wiring & rewiring: circuit development and plasticity in the sensory cortices
報告人：Y. Jennifer Sun, PhD，Lecturer, UCL Institute of Ophthalmology，Affiliate, Sainsbury Wellcome Centre
?The developing brain responds quickly to the sensory experience. In this talk, I will introduce my past research in studying the developmental processes that give rise to the highly specialized functions in auditory cortex, and in studying the structure-function changes that underlie the rapid ocular dominance plasticity in the developing visual cortex. I will also give an overview about the current and future research interest in my lab – that is, the synaptic and circuit mechanisms by which the mature brain circuits employ to regulate the balance between stability and plasticity. I will focus on the visual cortical circuit in the adult brain and present some work-in-progress studies in the lab to address these questions.
Dr Sun completed her undergraduate thesis from Peking University studying neuronal network and visual circuit assembly. Her PhD research at University of Southern California focused on circuit computation and sensory cortical development using both computational and systems approaches. During her postdoc training at UC San Francisco, Dr Sun worked with Drs Roger Nicoll and Michael Stryker to apply molecular techniques, electrophysiology, and 2-photon imaging to study the cellular and circuit mechanisms of neuroplasticity in developing and adult brain.
Dr Sun recently joined UCL Institute of Ophthalmology to start her independent research. The Visual Plasticity Lab studies how neuroplasticity in the visual systems is regulated through interaction in the local environment as well as crosstalk between different brain regions. We apply state-of-art imaging techniques, together with computational, physiological, pharmacological, and molecular manipulation, to identify the underlying biological basis of visual cortical plasticity.